| Daniel Christian | 28 Jul 2016 | @ Leicestershire Foxes | | 54* | 16 | 337.50 | 4 | 6 | 1.60 | 96.30 | 62.50 | 4.00 |
| David Hussey | 15 Jun 2011 | @ Durham Dynamos | | 54* | 24 | 225.00 | 2 | 4 | 4.00 | 59.26 | 25.00 | 4.00 |
| David Wiese | 9 Aug 2023 | @ Trent Rockets (Men) | | 54* | 25 | 216.00 | 3 | 4 | 3.57 | 66.67 | 28.00 | 7.00 |
| Alex Hales | 9 Jul 2015 | @ Derbyshire Falcons | | 54 | 35 | 154.29 | 7 | 1 | 4.38 | 62.96 | 22.86 | 1.00 |
| Dwayne Bravo | 23 Jun 2012 | @ England | | 54* | 36 | 150.00 | 1 | 3 | 9.00 | 40.74 | 11.11 | 5.00 |
| Gareth Cross | 19 Jun 2014 | @ Nottinghamshire Outlaws | | 54 | 38 | 142.11 | 5 | 1 | 6.33 | 48.15 | 15.79 | 3.00 |
| Alex Hales | 4 Jun 2015 | @ Leicestershire Foxes | | 54 | 42 | 128.57 | 4 | 3 | 6.00 | 62.96 | 16.67 | 2.00 |
| Robert Key | 16 Jul 2007 | @ Nottinghamshire Outlaws | | 54 | 43 | 125.58 | 2 | 2 | 10.75 | 37.04 | 9.30 | 2.00 |
| James Taylor | 18 Jul 2013 | @ Durham Dynamos | | 54 | 43 | 125.58 | 4 | 1 | 8.60 | 40.74 | 11.63 | 4.00 |
| Samit Patel | 2 Aug 2014 | @ Hampshire Royals | | 53* | 24 | 220.83 | 4 | 3 | 3.43 | 64.15 | 29.17 | 4.00 |
| Sam Hain | 11 Jun 2021 | @ Nottinghamshire Outlaws | | 53* | 28 | 189.29 | 2 | 4 | 4.67 | 60.38 | 21.43 | 4.00 |
| Adam Lyth | 31 Aug 2020 | @ Nottinghamshire Outlaws | | 53 | 29 | 182.76 | 7 | 2 | 3.22 | 75.47 | 31.03 | 2.00 |
| Robert Yates | 17 Jun 2022 | @ Nottinghamshire Outlaws | | 53 | 29 | 182.76 | 6 | 3 | 3.22 | 79.25 | 31.03 | 1.00 |
| Michael Lumb | 3 Jun 2016 | @ Lancashire Lightning | | 53 | 30 | 176.67 | 5 | 4 | 3.33 | 83.02 | 30.00 | 1.00 |
| Wahab Riaz | 2 Aug 2018 | @ Nottinghamshire Outlaws | | 53 | 31 | 170.97 | 4 | 4 | 3.88 | 75.47 | 25.81 | 3.00 |
| Eoin Morgan | 5 Sep 2019 | @ Nottinghamshire Outlaws | | 53 | 31 | 170.97 | 1 | 4 | 6.20 | 52.83 | 16.13 | 5.00 |
| Darren Maddy | 20 Jun 2003 | @ Nottinghamshire Outlaws | | 53 | 32 | 165.63 | 4 | 2 | 5.33 | 52.83 | 18.75 | 5.00 |
| Tillakaratne Dilshan | 7 Jun 2009 | @ Australia | | 53 | 32 | 165.63 | 10 | 0 | 3.20 | 75.47 | 31.25 | 1.00 |
| Dale Benkenstein | 24 May 2009 | @ Nottinghamshire Outlaws | | 53 | 33 | 160.61 | 6 | 3 | 3.67 | 79.25 | 27.27 | 6.00 |
| Mark Cosgrove | 28 Jul 2016 | @ Nottinghamshire Outlaws | | 53 | 34 | 155.88 | 6 | 1 | 4.86 | 56.60 | 20.59 | 1.00 |
| Ben Duckett | 1 Jul 2022 | @ Durham Dynamos | | 53* | 34 | 155.88 | 5 | 1 | 5.67 | 49.06 | 17.65 | 3.00 |
| Luis Reece | 26 May 2023 | @ Nottinghamshire Outlaws | | 53 | 35 | 151.43 | 4 | 3 | 5.00 | 64.15 | 20.00 | 1.00 |
| Alex Hales | 30 May 2023 | @ Yorkshire Carnegie | | 53 | 35 | 151.43 | 8 | 0 | 4.38 | 60.38 | 22.86 | 2.00 |
| Samit Patel | 10 Jul 2006 | @ Derbyshire Falcons | | 53* | 38 | 139.47 | 5 | 3 | 4.75 | 71.70 | 21.05 | 3.00 |
| Riki Wessels | 28 Jun 2012 | @ Durham Dynamos | | 53 | 38 | 139.47 | 5 | 1 | 6.33 | 49.06 | 15.79 | 3.00 |
| Stephen Fleming | 11 Aug 2006 | @ Leicestershire Foxes | | 53 | 39 | 135.90 | 8 | 0 | 4.88 | 60.38 | 20.51 | 2.00 |
| Michael Di Venuto | 10 Jul 2006 | @ Nottinghamshire Outlaws | | 53 | 41 | 129.27 | 8 | 0 | 5.13 | 60.38 | 19.51 | 1.00 |
| Michael Richardson | 5 Aug 2017 | @ Nottinghamshire Outlaws | | 53 | 41 | 129.27 | 5 | 0 | 8.20 | 37.74 | 12.20 | 3.00 |
| Steven Mullaney | 21 Jun 2010 | @ Northamptonshire Steelbacks | | 53 | 43 | 123.26 | 6 | 0 | 7.17 | 45.28 | 13.95 | 6.00 |
| Dawid Malan | 14 Aug 2024 | @ Trent Rockets (Men) | | 53* | 43 | 123.26 | 5 | 1 | 7.17 | 49.06 | 13.95 | 2.00 |
| Samit Patel | 4 Jun 2011 | @ Yorkshire Carnegie | | 52 | 23 | 226.09 | 4 | 4 | 2.88 | 76.92 | 34.78 | 5.00 |
| Aneurin Donald | 21 Jun 2024 | @ Nottinghamshire Outlaws | | 52 | 26 | 200.00 | 3 | 5 | 3.25 | 80.77 | 30.77 | 2.00 |
| Michael Di Venuto | 30 Jun 2005 | @ Nottinghamshire Outlaws | | 52 | 30 | 173.33 | 4 | 3 | 4.29 | 65.38 | 23.33 | 2.00 |
| Alex Hales | 18 Jul 2019 | @ Worcestershire Royals | | 52 | 34 | 152.94 | 3 | 3 | 5.67 | 57.69 | 17.65 | 2.00 |
| Joe Clarke | 27 May 2022 | @ Worcestershire Royals | | 52 | 34 | 152.94 | 6 | 2 | 4.25 | 69.23 | 23.53 | 1.00 |
| James Taylor | 27 Jun 2014 | @ Yorkshire Carnegie | | 52* | 38 | 136.84 | 5 | 1 | 6.33 | 50.00 | 15.79 | 5.00 |
| Samit Patel | 9 Jul 2015 | @ Derbyshire Falcons | | 52 | 38 | 136.84 | 3 | 2 | 7.60 | 46.15 | 13.16 | 4.00 |
| Adam Voges | 15 Jun 2008 | @ Derbyshire Falcons | | 52 | 39 | 133.33 | 6 | 0 | 6.50 | 46.15 | 15.38 | 4.00 |
| Riki Wessels | 19 May 2016 | @ Warwickshire Bears | | 52 | 41 | 126.83 | 4 | 2 | 6.83 | 53.85 | 14.63 | 2.00 |
| Rohit Sharma | 9 Jun 2009 | @ Ireland | | 52* | 45 | 115.56 | 4 | 1 | 9.00 | 42.31 | 11.11 | 2.00 |
| Dawid Malan | 15 Aug 2021 | @ Manchester Originals (Men) | | 52 | 46 | 113.04 | 7 | 0 | 6.57 | 53.85 | 15.22 | 2.00 |
| Ben Duckett | 11 Jun 2021 | @ Warwickshire Bears | | 51 | 27 | 188.89 | 7 | 2 | 3.00 | 78.43 | 33.33 | 4.00 |
| Adam Hose | 2 Jun 2023 | @ Nottinghamshire Outlaws | | 51* | 27 | 188.89 | 3 | 4 | 3.86 | 70.59 | 25.93 | 5.00 |
| Matthew Montgomery | 26 May 2023 | @ Derbyshire Falcons | | 51 | 29 | 175.86 | 6 | 1 | 4.14 | 58.82 | 24.14 | 4.00 |
| Joe Clarke | 1 Jul 2022 | @ Durham Dynamos | | 51 | 30 | 170.00 | 2 | 5 | 4.29 | 74.51 | 23.33 | 1.00 |
| Matthew Breetzke | 31 May 2024 | @ Nottinghamshire Outlaws | | 51* | 30 | 170.00 | 5 | 3 | 3.75 | 74.51 | 26.67 | 2.00 |
| Chris Nash | 31 Aug 2020 | @ Yorkshire Carnegie | | 51 | 32 | 159.38 | 5 | 2 | 4.57 | 62.75 | 21.88 | 1.00 |
| Jack Haynes | 31 May 2024 | @ Northamptonshire Steelbacks | | 51 | 32 | 159.38 | 6 | 2 | 4.00 | 70.59 | 25.00 | 3.00 |
| Will Smith | 30 Jun 2005 | @ Derbyshire Falcons | | 51 | 34 | 150.00 | 6 | 2 | 4.25 | 70.59 | 23.53 | 3.00 |
| Shahid Afridi | 17 Jun 2009 | @ South Africa | | 51 | 34 | 150.00 | 8 | 0 | 4.25 | 62.75 | 23.53 | 3.00 |
| Nathan Smith | 6 Jun 2024 | @ Nottinghamshire Outlaws | | 51* | 35 | 145.71 | 5 | 2 | 5.00 | 62.75 | 20.00 | 8.00 |
| Wayne Madsen | 9 Jul 2015 | @ Nottinghamshire Outlaws | | 51* | 37 | 137.84 | 5 | 0 | 7.40 | 39.22 | 13.51 | 4.00 |
| Dwayne Bravo | 9 Jun 2009 | @ Sri Lanka | | 51 | 38 | 134.21 | 5 | 2 | 5.43 | 62.75 | 18.42 | 6.00 |
| Sarah Bryce | 3 Aug 2024 | @ Trent Rockets (Women) | | 51* | 39 | 130.77 | 3 | 1 | 9.75 | 35.29 | 10.26 | 4.00 |
| D'Arcy Short | 24 Jul 2021 | @ Southern Brave (Men) | | 51* | 41 | 124.39 | 5 | 1 | 6.83 | 50.98 | 14.63 | 1.00 |
| Adam Voges | 21 Jun 2008 | @ Lancashire Lightning | | 51 | 42 | 121.43 | 6 | 0 | 7.00 | 47.06 | 14.29 | 2.00 |
| Alex Hales | 2 Aug 2014 | @ Hampshire Royals | | 51 | 45 | 113.33 | 4 | 2 | 7.50 | 54.90 | 13.33 | 1.00 |
| Wes Durston | 22 Jul 2013 | @ Nottinghamshire Outlaws | | 50* | 25 | 200.00 | 5 | 2 | 3.57 | 64.00 | 28.00 | 2.00 |
| Ian Ward | 18 Jul 2003 | @ Warwickshire Bears | | 50 | 28 | 178.57 | 8 | 1 | 3.11 | 76.00 | 32.14 | 1.00 |
| Michael Lumb | 27 Jun 2013 | @ Leicestershire Foxes | | 50 | 29 | 172.41 | 4 | 4 | 3.63 | 80.00 | 27.59 | 1.00 |
| Liam Livingstone | 13 Aug 2021 | @ Trent Rockets (Men) | | 50 | 31 | 161.29 | 4 | 3 | 4.43 | 68.00 | 22.58 | 3.00 |
| Greg Smith | 7 Aug 2016 | @ Essex Eagles | | 50 | 33 | 151.52 | 7 | 1 | 4.13 | 68.00 | 24.24 | 3.00 |
| Chris Cairns | 18 Jun 2008 | @ Leicestershire Foxes | | 50 | 38 | 131.58 | 6 | 0 | 6.33 | 48.00 | 15.79 | 5.00 |
| Joe Clarke | 2 Aug 2019 | @ Warwickshire Bears | | 50 | 40 | 125.00 | 5 | 1 | 6.67 | 52.00 | 15.00 | 1.00 |
| Gautam Gambhir | 5 Jun 2009 | @ Bangladesh | | 50 | 46 | 108.70 | 4 | 0 | 11.50 | 32.00 | 8.70 | 1.00 |
| Joe Clarke | 25 Aug 2019 | @ Yorkshire Carnegie | | 50 | 46 | 108.70 | 3 | 2 | 9.20 | 48.00 | 10.87 | 1.00 |
| David Hussey | 27 Jun 2013 | @ Leicestershire Foxes | | 49* | 25 | 196.00 | 4 | 2 | 4.17 | 57.14 | 24.00 | 5.00 |
| Stephen Fleming | 16 Jul 2007 | @ Kent Spitfires | | 49 | 28 | 175.00 | 7 | 1 | 3.50 | 69.39 | 28.57 | 2.00 |
| Colin Munro | 8 Jun 2023 | @ Durham Dynamos | | 49 | 28 | 175.00 | 6 | 2 | 3.50 | 73.47 | 28.57 | 3.00 |
| Karl Brown | 27 Jul 2018 | @ Nottinghamshire Outlaws | | 49 | 30 | 163.33 | 4 | 2 | 5.00 | 57.14 | 20.00 | 2.00 |
| Natalie Sciver | 1 Aug 2023 | @ Southern Brave (Women) | | 49 | 31 | 158.06 | 7 | 1 | 3.88 | 69.39 | 25.81 | 4.00 |
| Adam Voges | 17 Jun 2011 | @ Northamptonshire Steelbacks | | 49 | 32 | 153.13 | 7 | 0 | 4.57 | 57.14 | 21.88 | 3.00 |
| Alex Hales | 13 Sep 2020 | @ Derbyshire Falcons | | 49 | 32 | 153.13 | 9 | 0 | 3.56 | 73.47 | 28.13 | 2.00 |
| Steven Mullaney | 13 Aug 2021 | @ Birmingham Phoenix (Men) | | 49 | 33 | 148.48 | 2 | 3 | 6.60 | 53.06 | 15.15 | 4.00 |
| Craig Kieswetter | 6 Aug 2011 | @ Nottinghamshire Outlaws | | 49 | 37 | 132.43 | 5 | 1 | 6.17 | 53.06 | 16.22 | 2.00 |
| Riki Wessels | 26 Jul 2017 | @ Worcestershire Royals | | 49 | 43 | 113.95 | 2 | 2 | 10.75 | 40.82 | 9.30 | 1.00 |
| Ian Ward | 18 Jul 2003 | @ Gloucestershire Gladiators | | 49 | 48 | 102.08 | 5 | 1 | 8.00 | 53.06 | 12.50 | 1.00 |
| Farhaan Behardien | 28 Jul 2016 | @ Nottinghamshire Outlaws | | 48* | 26 | 184.62 | 6 | 1 | 3.71 | 62.50 | 26.92 | 4.00 |
| Chris Read | 29 Jun 2006 | @ Yorkshire Carnegie | | 48* | 28 | 171.43 | 5 | 2 | 4.00 | 66.67 | 25.00 | 5.00 |
| Joe Clarke | 31 May 2024 | @ Northamptonshire Steelbacks | | 48 | 30 | 160.00 | 6 | 2 | 3.75 | 75.00 | 26.67 | 1.00 |
| Ben Slater | 1 Jul 2021 | @ Leicestershire Foxes | | 48 | 31 | 154.84 | 6 | 1 | 4.43 | 62.50 | 22.58 | 3.00 |
| Tim Seifert | 5 Sep 2023 | @ England | | 48 | 32 | 150.00 | 6 | 2 | 4.00 | 75.00 | 25.00 | 2.00 |
| Tom Moores | 2 Aug 2018 | @ Derbyshire Falcons | | 48 | 34 | 141.18 | 4 | 3 | 4.86 | 70.83 | 20.59 | 2.00 |
| Tillakaratne Dilshan | 15 Jun 2009 | @ New Zealand | | 48 | 37 | 129.73 | 5 | 0 | 7.40 | 41.67 | 13.51 | 1.00 |
| Darren Lehmann | 29 Jun 2006 | @ Nottinghamshire Outlaws | | 48 | 38 | 126.32 | 9 | 0 | 4.22 | 75.00 | 23.68 | 3.00 |
| Adam Lyth | 25 Aug 2019 | @ Nottinghamshire Outlaws | | 48 | 39 | 123.08 | 7 | 0 | 5.57 | 58.33 | 17.95 | 1.00 |
| Sterre Kalis | 31 Jul 2024 | @ Trent Rockets (Women) | | 48* | 42 | 114.29 | 5 | 0 | 8.40 | 41.67 | 11.90 | 2.00 |
| Kieron Pollard | 6 Aug 2011 | @ Nottinghamshire Outlaws | | 47* | 25 | 188.00 | 2 | 4 | 4.17 | 68.09 | 24.00 | 5.00 |
| Shaun Marsh | 30 Jul 2017 | @ Nottinghamshire Outlaws | | 47 | 28 | 167.86 | 6 | 1 | 4.00 | 63.83 | 25.00 | 4.00 |
| Liam Livingstone | 6 Aug 2022 | @ Trent Rockets (Men) | | 47 | 28 | 167.86 | 1 | 5 | 4.67 | 72.34 | 21.43 | 4.00 |
| Joe Clarke | 21 Jun 2024 | @ Derbyshire Falcons | | 47 | 28 | 167.86 | 6 | 2 | 3.50 | 76.60 | 28.57 | 2.00 |
| Alex Hales | 2 Jul 2015 | @ Worcestershire Royals | | 47 | 29 | 162.07 | 5 | 3 | 3.63 | 80.85 | 27.59 | 2.00 |
| Jesse Ryder | 7 Aug 2016 | @ Nottinghamshire Outlaws | | 47 | 30 | 156.67 | 10 | 0 | 3.00 | 85.11 | 33.33 | 2.00 |
| Tom Moores | 27 May 2022 | @ Worcestershire Royals | | 47 | 31 | 151.61 | 2 | 3 | 6.20 | 55.32 | 16.13 | 5.00 |
| David Hussey | 24 Jun 2010 | @ Durham Dynamos | | 47* | 35 | 134.29 | 3 | 1 | 8.75 | 38.30 | 11.43 | 5.00 |
| Karl Brown | 3 Jun 2016 | @ Nottinghamshire Outlaws | | 47 | 36 | 130.56 | 6 | 1 | 5.14 | 63.83 | 19.44 | 3.00 |
| Brendan Taylor | 4 Jun 2015 | @ Leicestershire Foxes | | 47 | 39 | 120.51 | 6 | 0 | 6.50 | 51.06 | 15.38 | 4.00 |
| Niall O'Brien | 27 Jun 2013 | @ Nottinghamshire Outlaws | | 47 | 45 | 104.44 | 5 | 0 | 9.00 | 42.55 | 11.11 | 2.00 |
| Lizelle Lee | 15 Aug 2021 | @ Trent Rockets (Women) | | 47* | 45 | 104.44 | 5 | 1 | 7.50 | 55.32 | 13.33 | 1.00 |
| Billy Godleman | 17 Sep 2020 | @ Nottinghamshire Outlaws | | 47 | 47 | 100.00 | 5 | 0 | 9.40 | 42.55 | 10.64 | 2.00 |